Articles

Background: approximately 15% of colorectal carcinomas (CRC) display high
microsatellite instability (MSI-H).
These originate when the DNA mismatchrepair system, known as the MMR system, is dysfunctional,
which results in the accumulation of mutations caused by DNA polymerase, like point mutations, deletions
and in[...]

Objective: The aim of this review is to present the current varicocele treatment options in medical
practice. Methods: The authors performed a literature review using Medline regarding treatment of
varicocele. A number of 9 papers were considered suitable. Inclusion criteria consisted of papers written in
English wh[...]

One of the essential regulators of carcinogenesis is MicroRNA-21 (miR- 21). Yetlittlel1ighthasbeen1shedonitseffectiv1enessasatumor1markercomparedto1theconvention1alones. Comparing the diagnostic value of established tumor markers in breast cancer (BC) such as carcinoembryonic antigen (CEA) and CA153 with circulating le[...]

Parkinson's disease is a chronic degenerative neurological disease affecting the central nervous system and responsible for progressive disorders: slow movements, tremor, rigidity and cognitive disorders [1,2,3,4]. The symptoms of Parkinson's disease are related to the loss of about 70% of dopaminergic neurons. Data on[...]