Articles

Over the recent decades, the interest in nasal delivery as a feasible alternative to oral or parenteral administratio1n for some drugs is increased, because of the high permeability of the nasal epithelium, rapid drug absorption across this membrane and avoidance of hepatic first-pass metabolism. Therefore, it is impor[...]

Objective. The COVID-19 is considered to be a highly contagious pathogen. Since December 2019, an orthocoronavirinae virus has caused pneumonia identified as a new type of respiratory infection. This respiratory syndrome has quickly spread to all countries around the world to the point where WHO has declared it pandemi[...]

Background: approximately 15% of colorectal carcinomas (CRC) display high
microsatellite instability (MSI-H).
These originate when the DNA mismatchrepair system, known as the MMR system, is dysfunctional,
which results in the accumulation of mutations caused by DNA polymerase, like point mutations, deletions
and in[...]

One of the essential regulators of carcinogenesis is MicroRNA-21 (miR- 21). Yetlittlel1ighthasbeen1shedonitseffectiv1enessasatumor1markercomparedto1theconvention1alones. Comparing the diagnostic value of established tumor markers in breast cancer (BC) such as carcinoembryonic antigen (CEA) and CA153 with circulating le[...]