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ISSN: 0772-9200 - ISSN (print form): 2593-1431

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  • MICROSATELLITE INSTABILITY (MSI) AND BRAF MUTATION IN COLORECTAL CARCINOMAS

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    31-03-2020

    Tags : braf

    Category : Original articles

    Authors : Daniel Lerda, Edith Illescas, Jorge Labrador

    Background: approximately 15% of colorectal carcinomas (CRC) display high
    microsatellite instability (MSI-H).
    These originate when the DNA mismatchrepair system, known as the MMR system, is dysfunctional,
    which results in the accumulation of mutations caused by DNA polymerase, like point mutations, deletions
    and in[...]

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